Why I Chose GLP Therapy | Inflammation, Heart Health, and a New Approach to Preventative Care

GLP medications have become one of the most talked-about tools in modern medicine, often framed almost exclusively around weight loss or diabetes management.

But emerging research is revealing something far more compelling: GLP therapies may offer meaningful benefits for inflammation, metabolic balance, and cardiovascular health—even in people who are not diabetic and not overweight.

This evolving understanding is opening the door to a more personalized, preventative conversation about health, one that moves beyond treating disease after it appears and instead focuses on supporting the body earlier and more intentionally.

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Why I Chose GLP Therapy | Inflammation, Heart Health, and a New Approach to Preventative Care

But before getting into lived experience, it’s important to understand what GLPs actually are, where they came from, and what they were originally designed to do.

(Important note: I’m not a doctor or medical professional—just someone doing her due diligence when it comes to her health and sharing what I’ve learned along the way.)

What Is a GLP?

GLP stands for glucagon-like peptide-1, a hormone your body naturally produces in the gut. It’s released after eating and plays a key role in regulating several critical functions, including:

• Blood sugar levels
• Insulin secretion
• Appetite signaling
• Digestion speed
• Inflammatory responses

GLP-1 communicates directly with the brain, pancreas, heart, and immune system, making it far more than just an “appetite hormone.” When GLP-1 binds to its receptors, it helps the body respond to food more efficiently and maintain metabolic balance.

GLP medications—often referred to as GLP-1 receptor agonists—mimic this natural hormone but stay active in the body much longer, allowing for sustained effects.

How Long Have GLPs Been Around?

While GLPs may feel new thanks to social media and recent headlines, they are not new to medicine.

• GLP-1 receptor agonists were first developed in the early 2000s
• They were originally approved for the treatment of type 2 diabetes
• Weight loss was initially observed as a secondary effect, not the primary goal

For nearly two decades, GLPs were studied primarily for blood sugar regulation and insulin sensitivity. Only in recent years has research expanded into how these medications influence inflammation, cardiovascular markers, and overall metabolic health.

What Were GLPs Originally Used For?

GLP therapies were originally prescribed to help people with type 2 diabetes by:

• Improving insulin secretion
• Reducing glucagon release (which raises blood sugar)
• Slowing gastric emptying
• Stabilizing post-meal glucose spikes

These mechanisms made GLPs highly effective for glycemic control. Over time, researchers began noticing additional benefits that extended beyond blood sugar, including reductions in inflammatory markers and improvements in cardiovascular indicators.

The Emerging Role of GLPs in Inflammation

One of the most compelling areas of current research is the relationship between GLP-1 activity and inflammation.

Chronic, low-grade inflammation is now recognized as a root contributor to many modern health issues, including:

• Cardiovascular disease
• Autoimmune conditions
• Hormonal imbalance
• Metabolic dysfunction
• Accelerated aging

GLP-1 receptors are present on immune cells, which means GLPs can directly influence inflammatory pathways. Studies suggest GLP therapies may help:

• Reduce pro-inflammatory cytokines
• Improve endothelial function (the lining of blood vessels)
• Support healthier immune signaling

This anti-inflammatory potential is one reason GLPs are being explored beyond diabetes and weight management.

GLPs and Heart Health: What the Research Is Showing

Cardiovascular health is another area where GLPs are showing promise. Research indicates that GLP-1 receptor agonists may:

• Improve blood vessel flexibility
• Reduce oxidative stress
• Lower systemic inflammation that contributes to plaque formation
• Support healthier lipid metabolism

Several large-scale clinical trials have demonstrated reduced cardiovascular events in patients using GLP therapies, even when weight loss was not the primary variable. This suggests the heart-protective benefits of GLPs may be independent of body size.

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Why I Chose to Use a GLP Without Diabetes or Obesity

My decision to explore GLP therapy reflects a broader shift in medicine, from symptom-based treatment to proactive health optimization. After consulting with Dr. Susan Murrmann, I chose to explore a GLP paired with glutathione to support inflammation reduction, cardiovascular health, and hormonal balance during perimenopause.

After just one month of micro-dosing, I noticed significant changes. Inflammation visibly decreased—my socks no longer left deep indentations in my ankles, my mid-day bloating disappeared, and I woke up without puffy eyes or facial swelling. I genuinely felt like a new woman.

That said, I’m not relying on GLP therapy alone. I’ve also made intentional changes to my diet, added supportive supplements, and increased my movement and workouts.

It’s important to emphasize that GLPs are prescription medications and should always be used thoughtfully, under individualized medical guidance.

The Role of Glutathione Alongside GLPs

Dr. Murrmann also recommended pairing GLP therapy with glutathione, a powerful antioxidant often referred to as the body’s “master antioxidant.” Each evening, I take a gel packet of glutathione with water before bed to support recovery and inflammation control.

Glutathione plays a critical role in:

• Neutralizing oxidative stress
• Supporting liver detoxification
• Reducing inflammation
• Protecting cardiovascular and cellular health

When used together, GLPs and glutathione may offer complementary benefits—one supporting metabolic and hormonal signaling, the other targeting oxidative damage and inflammatory load.

A More Nuanced Conversation About GLPs

The biggest shift happening right now isn’t just in how GLPs are prescribed, it’s in how they’re understood. I’ll admit, when GLP therapy was first mentioned for heart health and inflammation, I paused. There was confusion, a little fear of the unknown, and a lot of curiosity.

After doing my own research—and reading Super Agers by Eric Topol, which was recommended to me by Dr. Murrmann, I felt informed and confident stepping into this new health chapter.

GLPs are no longer viewed solely as:

• “Diabetes drugs” or
• “Weight-loss injections”

They’re increasingly being studied as metabolic and inflammatory regulators with potential applications across a wide range of health goals.

GLP therapies represent a fascinating evolution in modern medicine. What began as a diabetes treatment is now being explored for its broader role in inflammation control, heart health, and metabolic balance—even among people who don’t fit traditional prescription categories.

As research continues to unfold, the conversation around GLPs is becoming less about aesthetics and more about long-term health, resilience, and quality of life—and I am absolutely here for it.

Please Note: I always strive to provide accurate and helpful information, but just a quick heads-up—I’m a blogger, not a doctor, lawyer, CPA, or any other kind of certified professional. I’m here to share my experiences and insights, but please make sure to use your own judgment and consult the right professionals when needed.  

Also, I accept monetary compensation through affiliate links, advertising, guest posts, and sponsored partnerships on this site, however I am very particular about the products I endorse and only do so when I am truly a fan of the quality and result of the product.